Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0TZ8C
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| Former ID |
DNC004509
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| Drug Name |
6-(2-Imidazol-1-yl-vinyl)-1H-quinolin-2-one
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| Synonyms |
CHEMBL347379; 6-(2-Imidazol-1-yl-vinyl)-1H-quinolin-2-one; SCHEMBL10461779
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C14H11N3O
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| Canonical SMILES |
C1=CC2=C(C=CC(=O)N2)C=C1C=CN3C=CN=C3
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| InChI |
1S/C14H11N3O/c18-14-4-2-12-9-11(1-3-13(12)16-14)5-7-17-8-6-15-10-17/h1-10H,(H,16,18)/b7-5+
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| InChIKey |
ULTZJAJIZBBKSG-FNORWQNLSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase 3A (PDE3A) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Purine metabolism | |||
| cGMP-PKG signaling pathway | ||||
| cAMP signaling pathway | ||||
| Morphine addiction | ||||
| Reactome | cGMP effects | |||
| G alpha (s) signalling events | ||||
| WikiPathways | miR-targeted genes in muscle cell - TarBase | |||
| miR-targeted genes in lymphocytes - TarBase | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 3,4-Dihydroquinolin-2(1H)-ones as combined inhibitors of thromboxane A2 synthase and cAMP phosphodiesterase. J Med Chem. 1992 Feb 21;35(4):620-8. | |||
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