Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0U2HZ
|
|||
Former ID |
DNC007888
|
|||
Drug Name |
6'-methylepibatidine
|
|||
Synonyms |
CHEMBL235261; 6'-methylepibatidine; 6''-methylepibatidine; SCHEMBL6359134
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C12H15ClN2
|
|||
Canonical SMILES |
CC1=C(C=CC(=N1)Cl)C2CC3CCC2N3
|
|||
InChI |
1S/C12H15ClN2/c1-7-9(3-5-12(13)14-7)10-6-8-2-4-11(10)15-8/h3,5,8,10-11,15H,2,4,6H2,1H3
|
|||
InChIKey |
CEIOZCMVGWULLM-UHFFFAOYSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Neuronal acetylcholine receptor alpha-4 (CHRNA4) | Target Info | Inhibitor | [1] |
Neuronal acetylcholine receptor beta-2 (CHRNB2) | Target Info | Inhibitor | [1] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Cholinergic synapse | ||||
Nicotine addiction | ||||
Panther Pathway | Nicotinic acetylcholine receptor signaling pathway | |||
Nicotine pharmacodynamics pathway | ||||
Reactome | Highly sodium permeable acetylcholine nicotinic receptors | |||
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors | ||||
Highly calcium permeable nicotinic acetylcholine receptors | ||||
WikiPathways | SIDS Susceptibility Pathways | |||
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
Nicotine Activity on Dopaminergic Neurons |
References | Top | |||
---|---|---|---|---|
REF 1 | Synthesis and nicotinic acetylcholine receptor binding properties of bridged and fused ring analogues of epibatidine. J Med Chem. 2007 Dec 13;50(25):6383-91. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.