Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0U3GZ
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| Former ID |
DNC006863
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| Drug Name |
2,5-dimethoxy-4-bromophenethylamine
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| Synonyms |
2,5-Dimethoxy-4-bromophenethylamine; 4-Bromo-2,5-dimethoxyphenethylamine; 66142-81-2; BDMPEA; 2-(4-Bromo-2,5-dimethoxyphenyl)ethylamine; 2C-B; 2-(4-Bromo-2,5-dimethoxyphenyl)ethanamine; Nexus; 4-Bromo-2,5-dimethoxyphenylethylamine; UNII-V77772N32H; Benzeneethanamine, 4-bromo-2,5-dimethoxy-; CHEMBL292821; 2-CB; CHEBI:189669; V77772N32H; Eros [Street Name]; Venus [Street Name]; Nexus [Street Name]; Nexus (pharmaceutical); Spectrum [Street Name]; NCGC00168259-02; Toonies [Street Name]dd; DEA No. 7392
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H14BrNO2
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| Canonical SMILES |
COC1=CC(=C(C=C1CCN)OC)Br
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| InChI |
1S/C10H14BrNO2/c1-13-9-6-8(11)10(14-2)5-7(9)3-4-12/h5-6H,3-4,12H2,1-2H3
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| InChIKey |
YMHOBZXQZVXHBM-UHFFFAOYSA-N
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| CAS Number |
CAS 66142-81-2
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:189669
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 2A receptor (HTR2A) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Gap junction | ||||
| Serotonergic synapse | ||||
| Inflammatory mediator regulation of TRP channels | ||||
| Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
| Reactome | Serotonin receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | Serotonin Receptor 2 and STAT3 Signaling | |||
| Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
| SIDS Susceptibility Pathways | ||||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 1-Aminomethylbenzocycloalkanes: conformationally restricted hallucinogenic phenethylamine analogues as functionally selective 5-HT2A receptor agoni... J Med Chem. 2006 Sep 21;49(19):5794-803. | |||
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