Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0U3PC
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| Former ID |
DNC012282
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| Drug Name |
1-Benzo[b]thiophen-2-yl-cycloheptylamine
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| Synonyms |
CHEMBL18811; NCI60_038329; 1-Benzo[b]thiophen-2-yl-cycloheptylamine; AC1L9GG6; CTK7D5124; ZINC1657601; BDBM50040194; 1-(benzothiophen-2-yl)cycloheptan-1-amine; 1-(1-benzothiophen-2-yl)cycloheptan-1-amine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H19NS
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| Canonical SMILES |
C1CCCC(CC1)(C2=CC3=CC=CC=C3S2)N
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| InChI |
1S/C15H19NS/c16-15(9-5-1-2-6-10-15)14-11-12-7-3-4-8-13(12)17-14/h3-4,7-8,11H,1-2,5-6,9-10,16H2
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| InChIKey |
BCBMINBNEZGMJJ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Dopamine transporter (DAT) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Dopaminergic synapse | |||
| Parkinson's disease | ||||
| Cocaine addiction | ||||
| Amphetamine addiction | ||||
| Alcoholism | ||||
| Panther Pathway | Adrenaline and noradrenaline biosynthesis | |||
| Parkinson disease | ||||
| Dopamine receptor mediated signaling pathway | ||||
| Pathway Interaction Database | Alpha-synuclein signaling | |||
| Reactome | Na+/Cl- dependent neurotransmitter transporters | |||
| WikiPathways | Monoamine Transport | |||
| NRF2 pathway | ||||
| Dopaminergic Neurogenesis | ||||
| Parkinsons Disease Pathway | ||||
| Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | ||||
| Neurotransmitter Clearance In The Synaptic Cleft | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and biological evaluation of 1-[1-(2-benzo[b]thienyl)cyclohexyl]piperidine homologues at dopamine-uptake and phencyclidine- and sigma-bin... J Med Chem. 1993 Apr 30;36(9):1188-93. | |||
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