Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0U4QZ
|
|||
Former ID |
DIB012712
|
|||
Drug Name |
EU-517
|
|||
Synonyms |
Mcl-1 inhibitors (cancer), Eutropics; BH3 mimetics/Mcl-1 inhibitors (cancer), Eutropics
Click to Show/Hide
|
|||
Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Investigative | [1] | |
Company |
Harvard Medical School
|
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) | Target Info | Inhibitor | [1] |
KEGG Pathway | PI3K-Akt signaling pathway | |||
MicroRNAs in cancer | ||||
NetPath Pathway | TCR Signaling Pathway | |||
Panther Pathway | Apoptosis signaling pathway | |||
CCKR signaling map ST | ||||
Pathway Interaction Database | E2F transcription factor network | |||
Direct p53 effectors | ||||
IL6-mediated signaling events | ||||
HIF-1-alpha transcription factor network | ||||
WikiPathways | Apoptosis | |||
miR-targeted genes in muscle cell - TarBase | ||||
miR-targeted genes in lymphocytes - TarBase | ||||
miR-targeted genes in leukocytes - TarBase | ||||
Apoptosis Modulation and Signaling |
References | Top | |||
---|---|---|---|---|
REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2847). |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.