Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0U4SS
|
|||
Former ID |
DIB010617
|
|||
Drug Name |
CD-160130
|
|||
Synonyms |
PDE-4 inhibitor (oral, B-CLL), Curacyte Discovery; PDE-4 inhibitor (oral, B-cell chronic lymphocytic leukemia), Curacyte Discovery
Click to Show/Hide
|
|||
Indication | Chronic lymphocytic leukaemia [ICD-11: 2A82.0; ICD-10: C83.0, C91.1] | Investigative | [1] | |
Company |
Curacyte AG
|
|||
Structure |
Download2D MOL |
|||
Formula |
C21H22N6O
|
|||
Canonical SMILES |
CCOC1=NC(=NC2=C1NC3=C2C=CC(=C3)C4=CC=NC=C4)N5CCNCC5
|
|||
InChI |
1S/C21H22N6O/c1-2-28-20-19-18(25-21(26-20)27-11-9-23-10-12-27)16-4-3-15(13-17(16)24-19)14-5-7-22-8-6-14/h3-8,13,23-24H,2,9-12H2,1H3
|
|||
InChIKey |
HFGHRUCCKVYFKL-UHFFFAOYSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Phosphodiesterase 4A (PDE4A) | Target Info | Inhibitor | [1] |
Phosphodiesterase 4B (PDE4B) | Target Info | Inhibitor | [2] | |
Phosphodiesterase 4D (PDE4D) | Target Info | Inhibitor | [3] | |
KEGG Pathway | Purine metabolism | |||
cAMP signaling pathway | ||||
Morphine addiction | ||||
NetPath Pathway | IL5 Signaling Pathway | |||
IL2 Signaling Pathway | ||||
Pathwhiz Pathway | Purine Metabolism | |||
Reactome | DARPP-32 events | |||
G alpha (s) signalling events | ||||
WikiPathways | G Protein Signaling Pathways | |||
Myometrial Relaxation and Contraction Pathways | ||||
TSH signaling pathway | ||||
Nuclear Receptors Meta-Pathway | ||||
Opioid Signalling |
References | Top | |||
---|---|---|---|---|
REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1300). | |||
REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1301). | |||
REF 3 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1303). |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.