Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0U7BW
|
|||
Former ID |
DAP000347
|
|||
Drug Name |
Carbachol
|
|||
Synonyms |
Carbach; Carbacholin; Carbacholine; Carbacholinum; Carbacholum; Carbacol; Carbacolina; Carbacolo; Carbamiotin; Carbamoylcholine; Carbastat; Carbochol; Carbocholin; Carbocholine; Carbyl; Carcholin; Coletyl; Doryl; Jestryl; Karbachol; Lentin; Lentine; Miostat; Moryl; Rilentol; Vasoperif; CARBACHOL CHLORIDE; Carbachol hydrochloride; Carbacholine chloride; Carbacholini chloridum; Carbacholinium chloratum; Carbacholum chloratum; Carbacolo [DCIT]; Carbaminocholine chloride; Carbaminoylcholine chloride; Carbamoylcholine chloride; Carbamylcholine chloride; Choline carbamate chloride; Choline chloride carbamate; Choline chlorine carbamate; Isopto Carbachol; Karbachol [Czech]; Karbamoylcholin chlorid; Karbamoylcholin chlorid [Czech]; Lentine [French]; Mistura C; C 4382; TL 457; C-1770; Carbacholum [INN-Latin]; Carbacol [INN-Spanish]; Carbamic acid, ester with choline chloride; Carbamoylcholine-hydrochloride; Carbastat (TN); Carboptic (TN); Choline chloride, carbamate; Doryl (VAN); Doryl (pharmaceutical); Gamma-Carbamoyl choline chloride; Isopto Carbachol (TN); Miostat (TN); Carbachol [INN:BAN:JAN]; Choline, chloride carbamate(ester); Choline, chloride, carbamate; P. V. Carbachol; Carbachol (JAN/USP/INN); Choline, chloride, carbamate, hydrochloride; Ethanaminium, 2-(aminocarbonyl)oxy-N,N,N-trimethyl-, chloride; Ethanaminium, 2-[(aminocarbonyl)oxy]-N,N,N-trimethyl-, chloride; Ethanaminium, 2-((aminocarbonyl)oxy)-N,N,N-trimethyl-, chloride; Ethanaminium, 2-((aminocarbonyl)oxy)-N,N,N-trimethyl-, chloride (1:1); (2-Carbamoyloxy-ethyl)-trimethyl-ammonium; (2-Carbamoyloxy-ethyl)-trimethyl-ammonium(Carbachol); (2-Carbamoyloxyethyl)trimethylammonium chloride; (2-Hydroxyethyl)trimethyl ammonium chloride carbamate; (2-Hydroxyethyl)trimethylammonium chloride carbamate; (carbachol)(2-Carbamoyloxy-ethyl)-trimethyl-ammonium; 2-((Aminocarbonyl)oxy)-N,N,N-trimethylethanaminium chloride; 2-((Aminocarbonyl)oxy)-N,N,N-trimethylethanaminum chloride; 2-(carbamoyloxy)-N,N,N-trimethylethanaminium chloride; 2-[(aminocarbonyl)oxy]-N,N,N-trimethylethanaminium chloride; 2-carbamoyloxyethyl(trimethyl)azanium chloride
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Glaucoma/ocular hypertension [ICD-11: 9C61; ICD-9: 365] | Approved | [1], [2] | |
Therapeutic Class |
Cardiotonic Agents
|
|||
Company |
Norvatis Phamaceuticals Corporation
|
|||
Structure |
Download2D MOL
|
|||
Formula |
C6H15ClN2O2
|
|||
Canonical SMILES |
C[N+](C)(C)CCOC(=O)N.[Cl-]
|
|||
InChI |
1S/C6H14N2O2.ClH/c1-8(2,3)4-5-10-6(7)9;/h4-5H2,1-3H3,(H-,7,9);1H
|
|||
InChIKey |
AIXAANGOTKPUOY-UHFFFAOYSA-N
|
|||
CAS Number |
CAS 51-83-2
|
|||
PubChem Compound ID | ||||
PubChem Substance ID |
833556, 4968909, 5051957, 5062074, 7886505, 7978854, 8151688, 11110943, 11110944, 11335900, 11361139, 11362928, 11365490, 11368052, 11371247, 11373861, 11376214, 11462111, 11466908, 11468028, 11483864, 11486616, 11487930, 11490140, 11492076, 11493908, 12125267, 26746619, 26756576, 29221712, 32964242, 46393347, 46508058, 47216796, 47291151, 47662302, 47736500, 47885436, 48334509, 48334510, 48334511, 49698976, 50069629, 50070662, 50110989, 57321369, 80594246, 90341139, 92308842, 103105591
|
|||
ChEBI ID |
CHEBI:3385
|
|||
ADReCS Drug ID | BADD_D00355 | |||
SuperDrug ATC ID |
N07AB01; S01EB02
|
|||
SuperDrug CAS ID |
cas=000051832
|
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Neuronal acetylcholine receptor alpha-2 (CHRNA2) | Target Info | Antagonist | [3] |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Panther Pathway | Nicotinic acetylcholine receptor signaling pathway | |||
Reactome | Highly calcium permeable postsynaptic nicotinic acetylcholine receptors | |||
Highly calcium permeable nicotinic acetylcholine receptors | ||||
WikiPathways | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell |
References | Top | |||
---|---|---|---|---|
REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 298). | |||
REF 2 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 070292. | |||
REF 3 | Synergy between pairs of competitive antagonists at adult human muscle acetylcholine receptors. Anesth Analg. 2008 Aug;107(2):525-33. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.