Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0U8OS
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| Former ID |
DNC010689
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| Drug Name |
N-(3-(3-methoxyphenyl)propyl)acetamide
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| Synonyms |
N-[3-(3-methoxyphenyl)propyl]acetamide; CHEMBL50398; N-(3-(3-methoxyphenyl)propyl)acetamide; Acetamide, N-[3-(3-methoxyphenyl)propyl]-; SCHEMBL8928104; BDBM50049516; 174688-91-6
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C12H17NO2
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| Canonical SMILES |
CC(=O)NCCCC1=CC(=CC=C1)OC
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| InChI |
1S/C12H17NO2/c1-10(14)13-8-4-6-11-5-3-7-12(9-11)15-2/h3,5,7,9H,4,6,8H2,1-2H3,(H,13,14)
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| InChIKey |
LOVJFNACINEBJW-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Melatonin receptor type 1A (MTNR1A) | Target Info | Inhibitor | [1] |
| Melatonin receptor type 1B (MTNR1B) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Circadian entrainment | ||||
| Reactome | Class A/1 (Rhodopsin-like receptors) | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Small Ligand GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis of substituted N-[3-(3-methoxyphenyl)propyl] amides as highly potent MT(2)-selective melatonin ligands. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2582-5. | |||
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