Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0U9WS
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| Former ID |
DIB016686
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| Drug Name |
LEO-32731
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| Synonyms |
LP0058
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| Indication | Plaque psoriasis [ICD-11: EA90.0; ICD-10: L40.0] | Phase 2 | [1] | |
| Psoriasis vulgaris [ICD-11: EA90; ICD-9: 696] | Phase 1 | [2] | ||
| Company |
LEO Pharma A/S
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| Structure |
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Download2D MOL |
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| Formula |
C19H15Cl2F2NO7S
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| Canonical SMILES |
C1CS(=O)(=O)CCC12OC3=C(C=CC(=C3O2)OC(F)F)C(=O)CC4=C(C=[N+](C=C4Cl)[O-])Cl
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| InChI |
1S/C19H15Cl2F2NO7S/c20-12-8-24(26)9-13(21)11(12)7-14(25)10-1-2-15(29-18(22)23)17-16(10)30-19(31-17)3-5-32(27,28)6-4-19/h1-2,8-9,18H,3-7H2
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| InChIKey |
ZININGNRPUGNSL-UHFFFAOYSA-N
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| CAS Number |
CAS 1353546-86-7
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase 4 (PDE4) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
| REF 2 | ClinicalTrials.gov (NCT01310049) LEO 32731 - A Study in Healthy Male Subjects. U.S. National Institutes of Health. | |||
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