Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0UO2Z
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| Former ID |
DNC010834
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| Drug Name |
4-(2-(4-Cyclohexylphenylamino)ethyl)-1H-imidazole
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| Synonyms |
CHEMBL1098229; 4-(2-(4-Cyclohexylphenylamino)ethyl)-1H-imidazole
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C17H23N3
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| Canonical SMILES |
C1CCC(CC1)C2=CC=C(C=C2)NCCC3=CN=CN3
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| InChI |
1S/C17H23N3/c1-2-4-14(5-3-1)15-6-8-16(9-7-15)19-11-10-17-12-18-13-20-17/h6-9,12-14,19H,1-5,10-11H2,(H,18,20)
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| InChIKey |
GEYDSVZUDGXVCV-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine H3 receptor (H3R) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Histamine receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Monoamine Transport | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Role of hydrophobic substituents on the terminal nitrogen of histamine in receptor binding and agonist activity: development of an orally active hi... J Med Chem. 2010 May 13;53(9):3840-4. | |||
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