Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0UX4A
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| Former ID |
DIB001674
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| Drug Name |
HU-433
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| Synonyms |
CB2 activator (osteoporosis); CB2 activator (osteoporosis), Yissum
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| Indication | Osteoporosis [ICD-11: FB83.0; ICD-10: M85.8] | Investigative | [1] | |
| Company |
Yissum Research Development Co
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| Structure |
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Download2D MOL |
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| Formula |
C27H42O3
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| Canonical SMILES |
CCCCCCC(C)(C)C1=CC(=C(C(=C1)OC)C2C=C(C3CC2C3(C)C)CO)OC
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| InChI |
1S/C27H42O3/c1-8-9-10-11-12-26(2,3)19-14-23(29-6)25(24(15-19)30-7)20-13-18(17-28)21-16-22(20)27(21,4)5/h13-15,20-22,28H,8-12,16-17H2,1-7H3/t20?,21-,22+/m0/s1
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| InChIKey |
CFMRIVODIXTERW-JTGIGXABSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cannabinoid receptor 2 (CB2) | Target Info | Activator | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Class A/1 (Rhodopsin-like receptors) | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Small Ligand GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 57). | |||
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