Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0UZ8R
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| Former ID |
DNC005476
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| Drug Name |
1,2-Bis-(4-methoxy-phenyl)-ethane-1,2-dione
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| Synonyms |
4,4'-Dimethoxybenzil; 1226-42-2; p-Anisil; Anisil; 1,2-bis(4-methoxyphenyl)ethane-1,2-dione; Bis(4-methoxyphenyl)ethanedione; Ethanedione, bis(4-methoxyphenyl)-; Di-p-anisoyl; p,p'-Dimethoxybenzil; 1,2-ethanedione, 1,2-bis(4-methoxyphenyl)-; YNANGXWUZWWFKX-UHFFFAOYSA-N; MFCD00008405; 1,2-Bis(4-methoxyphenyl)-1,2-ethanedione; 1,2-bis(4-methoxyphenyl)-ethane-1,2-dione; AE-641/01115007; W-108428; 4,4'-Dimethoxybenzil, 99+%; EINECS 214-960-5; NSC 19218; ACMC-1BZIL; p-Anisil; Di-p-anisoyl; 4,4\'-Dimethoxybenzil
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C16H14O4
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| Canonical SMILES |
COC1=CC=C(C=C1)C(=O)C(=O)C2=CC=C(C=C2)OC
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| InChI |
1S/C16H14O4/c1-19-13-7-3-11(4-8-13)15(17)16(18)12-5-9-14(20-2)10-6-12/h3-10H,1-2H3
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| InChIKey |
YNANGXWUZWWFKX-UHFFFAOYSA-N
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| CAS Number |
CAS 1226-42-2
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Liver carboxylesterase (CES1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Drug metabolism - other enzymes | |||
| Metabolic pathways | ||||
| Pathway Interaction Database | E2F transcription factor network | |||
| WikiPathways | NRF2 pathway | |||
| Nuclear Receptors Meta-Pathway | ||||
| Heroin metabolism | ||||
| Irinotecan Pathway | ||||
| Fluoropyrimidine Activity | ||||
| Phase I biotransformations, non P450 | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Identification and characterization of novel benzil (diphenylethane-1,2-dione) analogues as inhibitors of mammalian carboxylesterases. J Med Chem. 2005 Apr 21;48(8):2906-15. | |||
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