Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0V0DI
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| Former ID |
DIB006887
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| Drug Name |
CT-2584
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| Synonyms |
Apra (Cell Therapeutics, US, US); 1-[11-(Dodecylamino)-10-hydroxyundecyl]-3,7-dimethylxanthine
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| Drug Type |
Small molecular drug
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C00-D48; ICD-9: 140-199, 210-229] | Phase 3 | [1] | |
| Company |
Cell Therapeutics
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| Structure |
 |
Download2D MOL |
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| Formula |
C30H55N5O3
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| Canonical SMILES |
CCCCCCCCCCCCNCC(CCCCCCCCCN1C(=O)C2=C(N=CN2C)N(C1=O)C)O
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| InChI |
1S/C30H55N5O3/c1-4-5-6-7-8-9-10-13-16-19-22-31-24-26(36)21-18-15-12-11-14-17-20-23-35-29(37)27-28(32-25-33(27)2)34(3)30(35)38/h25-26,31,36H,4-24H2,1-3H3
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| InChIKey |
MZNMZWZGUGFQJP-UHFFFAOYSA-N
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| CAS Number |
CAS 166981-13-1
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cholinephosphate cytidylyltransferase (PCYT1B) | Target Info | Modulator | [1] |
| KEGG Pathway | Glycerophospholipid metabolism | |||
| Metabolic pathways | ||||
| Choline metabolism in cancer | ||||
| Pathwhiz Pathway | Phospholipid Biosynthesis | |||
| WikiPathways | Acetylcholine Synthesis | |||
| Glycerophospholipid biosynthesis | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Pharmacological inhibition of phosphatidylcholine biosynthesis is associated with induction of phosphatidylinositol accumulation and cytolysis of neoplastic cell lines. Cancer Res. 2000 Sep 15;60(18):5204-13. | |||
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