Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0V1RX
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| Former ID |
DNC000950
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| Drug Name |
Mivazerol
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| Synonyms |
125472-02-8; Mivazerol [INN]; UNII-W5P1SSA8KD; Mivazerolum [INN-Latin]; alpha-Imidazol-4-yl-2,3-cresotamide; 2-HYDROXY-3-(1H-IMIDAZOL-4-YLMETHYL)-BENZAMIDE; W5P1SSA8KD; 3-((1H-Imidazol-4-yl)methyl)-2-hydroxybenzamide; Benzamide,2-hydroxy-3-(1H-imidazol-5-ylmethyl)-; Mivazerolum; ucb 22073; mivazerol[inn]; ACMC-20mrix; AC1L1TX2; 2-hydroxy-3-(1H-imidazol-5-ylmethyl)benzamide; SCHEMBL593707; SCHEMBL8097939; AC1Q5D40; CHEMBL2105189; CTK4B4380; DTXSID30154782; ZINC4674535; 3-((1H-imidazol-4-yl)methyl)-2-hydroxybenzamide; Closantel 6
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| Drug Type |
Small molecular drug
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| Indication | Angina pectoris [ICD-11: BA40; ICD-9: 413] | Discontinued in Phase 3 | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C11H11N3O2
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| Canonical SMILES |
C1=CC(=C(C(=C1)C(=O)N)O)CC2=CN=CN2
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| InChI |
1S/C11H11N3O2/c12-11(16)9-3-1-2-7(10(9)15)4-8-5-13-6-14-8/h1-3,5-6,15H,4H2,(H2,12,16)(H,13,14)
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| InChIKey |
RLHGFJMGWQXPBW-UHFFFAOYSA-N
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| CAS Number |
CAS 125472-02-8
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| PubChem Compound ID | ||||
| PubChem Substance ID |
7980009, 8187051, 14822582, 43118131, 50064295, 52418645, 57314110, 85210015, 104321635, 117561609, 125686955, 129145721, 134222089, 134339875, 134340231, 135025545, 135946901, 137229308, 137249447, 139582175, 160687180, 162222726, 162383618, 162782698, 172658056, 179149745, 198957048, 215778965, 223561049, 226897517, 233638133, 252332753
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adrenergic receptor Alpha-2 (ADRA2) | Target Info | Agonist | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002725) | |||
| REF 2 | Alpha-2 and imidazoline receptor agonists. Their pharmacology and therapeutic role. Anaesthesia. 1999 Feb;54(2):146-65. | |||
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