Drug Information
Drug General Information | Top | |||
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Drug ID |
D0V3ZN
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Former ID |
DIB016148
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Drug Name |
AG-SPT201
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Synonyms |
SPT201; S-pantoprazole sodium trihydrate (ulcer), Ahn-Gook; (S)-pantoprazole sodium trihydrate
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Indication | Ulcerative colitis [ICD-11: DD71; ICD-9: 556] | Phase 3 | [1] | |
Company |
Ahn-Gook Pharmaceuticals Co Ltd
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Structure |
Download2D MOL |
Target and Pathway | Top | |||
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Target(s) | Gastric H(+)/K(+) ATPase alpha (ATP4A) | Target Info | Modulator | [2] |
KEGG Pathway | Oxidative phosphorylation | |||
Collecting duct acid secretion | ||||
Gastric acid secretion | ||||
Pathwhiz Pathway | Gastric Acid Production | |||
Reactome | Ion transport by P-type ATPases | |||
WikiPathways | Iron uptake and transport | |||
Secretion of Hydrochloric Acid in Parietal Cells |
References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT01400945) Efficacy Study of AGSPT201 Tablet to Treat Gastroesophageal Reflux Disease. U.S. National Institutes of Health. | |||
REF 2 | Effects of pantoprazole, a novel H+/K+-ATPase inhibitor, on duodenal ulcerogenic and healing responses in rats: a comparative study with omeprazole and lansoprazole. J Gastroenterol Hepatol. 1999 Mar;14(3):251-7. |
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