Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0V4XG
|
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| Former ID |
DIB009852
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| Drug Name |
GSK2793660
|
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| Synonyms |
2793660
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| Indication | Bronchiectasis [ICD-11: CA24; ICD-10: J47] | Phase 1 | [1] | |
| Company |
Glaxosmithkline
|
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Dipeptidyl peptidase I (CTSC) | Target Info | Modulator | [1] |
| KEGG Pathway | Lysosome | |||
| NetPath Pathway | IL2 Signaling Pathway | |||
| IL4 Signaling Pathway | ||||
| TGF_beta_Receptor Signaling Pathway | ||||
| Reactome | COPII (Coat Protein 2) Mediated Vesicle Transport | |||
| MHC class II antigen presentation | ||||
| Cargo concentration in the ER | ||||
| WikiPathways | miR-targeted genes in muscle cell - TarBase | |||
| miR-targeted genes in lymphocytes - TarBase | ||||
| miR-targeted genes in leukocytes - TarBase | ||||
| miR-targeted genes in epithelium - TarBase | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT02058407) A Study to Evaluate the Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD) and Food Effect of Single or Repeat Doses of GSK2793660 in Healthy Subjects. U.S. National Institutes of Health. | |||
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