Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0V7TA
|
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| Former ID |
DNC009982
|
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| Drug Name |
2-phenyl-2H-pyrazolo[4,3-d]pyrimidin-7(6H)-one
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C11H8N4O
|
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| Canonical SMILES |
C1=CC=C(C=C1)N2C=C3C(=N2)C(=O)NC=N3
|
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| InChI |
1S/C11H8N4O/c16-11-10-9(12-7-13-11)6-15(14-10)8-4-2-1-3-5-8/h1-7H,(H,12,13,16)
|
|||
| InChIKey |
OQHWVAQCLKFQMO-UHFFFAOYSA-N
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenosine A3 receptor (ADORA3) | Target Info | Inhibitor | [1] |
| Reactome | Adenosine P1 receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Nucleotide GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 2-Phenylpyrazolo[4,3-d]pyrimidin-7-one as a new scaffold to obtain potent and selective human A3 adenosine receptor antagonists: new insights into ... J Med Chem. 2009 Dec 10;52(23):7640-52. | |||
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