Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0V7VF
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| Former ID |
DNC009398
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| Drug Name |
N-(3-(3-methoxyphenyl)-3-phenylallyl)acetamide
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| Synonyms |
CHEMBL218708; N-(3-(3-methoxyphenyl)-3-phenylallyl)acetamide; BDBM50241105; AKOS030564511
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C18H19NO2
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| Canonical SMILES |
CC(=O)NCC=C(C1=CC=CC=C1)C2=CC(=CC=C2)OC
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| InChI |
1S/C18H19NO2/c1-14(20)19-12-11-18(15-7-4-3-5-8-15)16-9-6-10-17(13-16)21-2/h3-11,13H,12H2,1-2H3,(H,19,20)/b18-11+
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| InChIKey |
SJNURYXTMIYOKB-WOJGMQOQSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Melatonin receptor type 1A (MTNR1A) | Target Info | Inhibitor | [1] |
| Melatonin receptor type 1B (MTNR1B) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Circadian entrainment | ||||
| Reactome | Class A/1 (Rhodopsin-like receptors) | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Small Ligand GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 2-[(2,3-dihydro-1H-indol-1-yl)methyl]melatonin analogues: a novel class of MT2-selective melatonin receptor antagonists. J Med Chem. 2009 Feb 12;52(3):826-33. | |||
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