Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0V8HA
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| Former ID |
DAP000027
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| Drug Name |
Mecamylamine
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| Synonyms |
Mecamilamina; Mecamine; Mecamylaminum; Mekamine; Mevasine; Revertina; Versamine; Inversine hydrochloride; Mecamilamina [DCIT]; Mecamilamina [Italian]; Mevasin hydrochloride; Inversine (TN); Mecamylamine [INN:BAN]; Mecamylaminum [INN-Latin]; N-Methyl-2-isocamphanamine; N,2,3,3-Tetramethyl-2-norbornamine; N,2,3,3-Tetramethyl-2-norcamphanamine; N,2,2,3-tetramethylbicyclo[2.2.1]heptan-3-amine; N,2,3,3-Tetramethylbicyclo[2.2.1]heptan-2-amine; 2-Methylamino-2,3,3-trimethylnorbornane; 2-Methylaminoisocamphane; 3-Methylaminoisocamphane; 3-Methylaminoisokamfan; 3-Methylaminoisokamfan [Czech]; 3-beta-Methylamino-2,2,3-trimethylbicyclo(2.2.1)heptane
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| Drug Type |
Small molecular drug
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| Indication | Essential hypertension [ICD-11: BA00; ICD-10: I10] | Approved | [1] | |
| Therapeutic Class |
Antihypertensive Agents
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| Company |
Mecamylamine
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| Structure |
 |
Download2D MOL |
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| Formula |
C11H21N
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| Canonical SMILES |
CC1(C2CCC(C2)C1(C)NC)C
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| InChI |
1S/C11H21N/c1-10(2)8-5-6-9(7-8)11(10,3)12-4/h8-9,12H,5-7H2,1-4H3
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| InChIKey |
IMYZQPCYWPFTAG-UHFFFAOYSA-N
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| CAS Number |
CAS 60-40-2
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9714, 3249412, 4782131, 8152523, 11342007, 11362190, 11363198, 11365760, 11368322, 11371612, 11374952, 11376484, 11467139, 11468259, 11486847, 11487592, 11490552, 11493071, 11494118, 14748127, 26755706, 29223143, 46508607, 47365386, 47365387, 47365388, 47440440, 47440441, 47885580, 48110632, 48416199, 49698966, 49998070, 50111169, 50813825, 53788079, 57322103, 90341710, 103164508, 103826601, 103957127, 104171190, 104305231, 108209719, 118270204, 124589602, 124750040, 124880783, 125823670, 128191225
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| ChEBI ID |
CHEBI:6706
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| ADReCS Drug ID | BADD_D01356 ; BADD_D01357 | |||
| SuperDrug ATC ID |
C02BB01
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| SuperDrug CAS ID |
cas=000060402
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Nicotinic acetylcholine receptor (nAChR) | Target Info | Antagonist | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | Mecamylamine (Inversine): an old antihypertensive with new research directions. J Hum Hypertens. 2002 Jul;16(7):453-7. | |||
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