Drug Information
Drug General Information | Top | |||
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Drug ID |
D0V9NE
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Former ID |
DNC002674
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Drug Name |
Tanaproget
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Synonyms |
Tanaproget; 304853-42-7; NSP-989; UNII-W9F9H8GXWR; W9F9H8GXWR; 5-(4,4-Dimethyl-2-thioxo-1,4-dihydro-2H-3,1-benzoxazin-6-yl)-1-methyl-1H-pyrrole-2-carbonitrile; T98; Tanaproget [USAN:INN]; 1zuc; NSP 989; Tanaproget (USAN/INN); AC1NA08O; SCHEMBL62188; CHEMBL539163; GTPL7416; DTXSID00184556; PYVFWTPEBMRKSR-UHFFFAOYSA-N; ZINC6245719; BDBM50375821; AKOS030526776; SB17247; DB04787; CS-1550; NSP-989;NSP 989;NSP989; HY-15606; KB-145966; FT-0735521; W-5758; D06003
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Drug Type |
Small molecular drug
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Indication | Estrogen deficiency [ICD-11: FB83.0Y; ICD-10: E28.39] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C16H15N3OS
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Canonical SMILES |
CC1(C2=C(C=CC(=C2)C3=CC=C(N3C)C#N)NC(=S)O1)C
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InChI |
1S/C16H15N3OS/c1-16(2)12-8-10(4-6-13(12)18-15(21)20-16)14-7-5-11(9-17)19(14)3/h4-8H,1-3H3,(H,18,21)
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InChIKey |
PYVFWTPEBMRKSR-UHFFFAOYSA-N
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CAS Number |
CAS 304853-42-7
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Progesterone receptor (PGR) | Target Info | Inhibitor | [2] |
KEGG Pathway | Oocyte meiosis | |||
Progesterone-mediated oocyte maturation | ||||
Pathway Interaction Database | Cellular roles of Anthrax toxin | |||
Reactome | Nuclear signaling by ERBB4 | |||
Nuclear Receptor transcription pathway | ||||
WikiPathways | Ovarian Infertility Genes | |||
Signaling by ERBB4 | ||||
Nuclear Receptors |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7416). | |||
REF 2 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. |
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