Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0V9US
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| Former ID |
DNC011634
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| Drug Name |
6-Phenylsulfanylmethyl-pteridine-2,4-diamine
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| Synonyms |
NSC232965; 57963-58-3; UNII-D5VU87D2MN; D5VU87D2MN; 2,4-Diamino-6-phenylthiomethyl-pteridine; CHEMBL279243; 6-(phenylsulfanylmethyl)pteridine-2,4-diamine; 2,4-Pteridinediamine, 6-((phenylthio)methyl)-; 2,4-Pteridinediamine, 6-[(phenylthio)methyl]-; NSC 232965; AC1L7PXP; 6-Phenylsulfanylmethyl-pteridine-2,4-diamine; ZINC5088; SCHEMBL11630631; DTXSID30206699; BDBM50049602; NSC-232965; 6-(Phenylthiomethyl)pteridine-2,4-diamine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C13H12N6S
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| Canonical SMILES |
C1=CC=C(C=C1)SCC2=CN=C3C(=N2)C(=NC(=N3)N)N
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| InChI |
1S/C13H12N6S/c14-11-10-12(19-13(15)18-11)16-6-8(17-10)7-20-9-4-2-1-3-5-9/h1-6H,7H2,(H4,14,15,16,18,19)
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| InChIKey |
ZJOATKLQTCGUSP-UHFFFAOYSA-N
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| CAS Number |
CAS 57963-58-3
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Polypeptide deformylase (PDF) | Target Info | Inhibitor | [1] |
| Pathwhiz Pathway | Folate Metabolism | |||
| Pterine Biosynthesis | ||||
| Reactome | E2F mediated regulation of DNA replication | |||
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | ||||
| Metabolism of folate and pterines | ||||
| G1/S-Specific Transcription | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Nonclassical 2,4-diamino-8-deazafolate analogues as inhibitors of dihydrofolate reductases from rat liver, Pneumocystis carinii, and Toxoplasma gon... J Med Chem. 1996 Apr 26;39(9):1836-45. | |||
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