Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0VA4Y
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| Former ID |
DCL000928
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| Drug Name |
Phentermine+topiramate
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| Synonyms |
Qnexa (TN)
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| Drug Type |
Small molecular drug
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| Indication | Obesity [ICD-11: 5B81; ICD-10: E66; ICD-9: 278] | Phase 3 | [1] | |
| Company |
Vivus
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| Structure |
 |
Download2D MOL |
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| Formula |
C22H36N2O8S
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| Canonical SMILES |
CC1(OC2COC3(C(C2O1)OC(O3)(C)C)COS(=O)(=O)N)C.CC(C)(CC1=CC=CC=C1)N
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| InChI |
1S/C12H21NO8S.C10H15N/c1-10(2)18-7-5-16-12(6-17-22(13,14)15)9(8(7)19-10)20-11(3,4)21-12;1-10(2,11)8-9-6-4-3-5-7-9/h7-9H,5-6H2,1-4H3,(H2,13,14,15);3-7H,8,11H2,1-2H3/t7-,8-,9?,12+;/m1./s1
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| InChIKey |
PWDLDBWXTVILPC-QGGVPXFVSA-N
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| CAS Number |
CAS 960078-81-3
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| SuperDrug ATC ID |
C01CA11
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| SuperDrug CAS ID |
cas=000100925
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Carbonic anhydrase (CA) | Target Info | Inhibitor | [2] |
| Gamma-aminobutyric acid receptor (GAR) | Target Info | Modulator | [2] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Adjunctive topiramate enhances the risk of hypothermia associated with valproic acid therapy. J Clin Pharm Ther. 2008 Oct;33(5):513-9. | |||
| REF 2 | Anti-obesity drugs. Expert Opin Pharmacother. 2008 Jun;9(8):1339-50. | |||
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