Drug Information
Drug General Information | Top | |||
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Drug ID |
D0VL3R
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Former ID |
DNC009633
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Drug Name |
3-(5,6,7,8-Tetrahydronaphthalen-2-yl)pyridine
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Synonyms |
CHEMBL461457; 3-(5,6,7,8-Tetrahydronaphthalen-2-yl)pyridine; SCHEMBL8081400; ZINC40863212
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C15H15N
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Canonical SMILES |
C1CCC2=C(C1)C=CC(=C2)C3=CN=CC=C3
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InChI |
1S/C15H15N/c1-2-5-13-10-14(8-7-12(13)4-1)15-6-3-9-16-11-15/h3,6-11H,1-2,4-5H2
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InChIKey |
WGNJGUOGXBTDMP-UHFFFAOYSA-N
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CAS Number |
CAS 1092522-77-4
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Steroid 11-beta-hydroxylase (CYP11B1) | Target Info | Inhibitor | [1] |
BioCyc | Superpathway of steroid hormone biosynthesis | |||
Glucocorticoid biosynthesis | ||||
Mineralocorticoid biosynthesis | ||||
KEGG Pathway | Steroid hormone biosynthesis | |||
Metabolic pathways | ||||
Pathwhiz Pathway | Steroidogenesis | |||
Reactome | Glucocorticoid biosynthesis | |||
Endogenous sterols | ||||
WikiPathways | Metapathway biotransformation | |||
Oxidation by Cytochrome P450 | ||||
Metabolism of steroid hormones and vitamin D | ||||
Corticotropin-releasing hormone |
References | Top | |||
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REF 1 | In vivo active aldosterone synthase inhibitors with improved selectivity: lead optimization providing a series of pyridine substituted 3,4-dihydro-... J Med Chem. 2008 Dec 25;51(24):8077-87. |
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