Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0W1CC
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| Former ID |
DNC013046
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| Drug Name |
(R)-(+)-(4,5,6-trimethoxyindan-1-yl)methanamine
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| Synonyms |
CHEMBL379780; 890309-57-6; Jimscaline; (R)-(+)-(4,5,6-trimethoxyindan-1-yl)methanamine; CTK2I1398; DTXSID30470414; ZINC35569551; BDBM50190615; 1H-Indene-1-methanamine, 2,3-dihydro-4,5,6-trimethoxy-, (1R)-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C13H19NO3
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| Canonical SMILES |
COC1=C(C(=C2CCC(C2=C1)CN)OC)OC
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| InChI |
1S/C13H19NO3/c1-15-11-6-10-8(7-14)4-5-9(10)12(16-2)13(11)17-3/h6,8H,4-5,7,14H2,1-3H3/t8-/m0/s1
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| InChIKey |
AFTIZGHFDCOQFS-QMMMGPOBSA-N
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| CAS Number |
CAS 890309-57-6
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 2A receptor (HTR2A) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Gap junction | ||||
| Serotonergic synapse | ||||
| Inflammatory mediator regulation of TRP channels | ||||
| Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
| Reactome | Serotonin receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | Serotonin Receptor 2 and STAT3 Signaling | |||
| Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
| SIDS Susceptibility Pathways | ||||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | C-(4,5,6-trimethoxyindan-1-yl)methanamine: a mescaline analogue designed using a homology model of the 5-HT2A receptor. J Med Chem. 2006 Jul 13;49(14):4269-74. | |||
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