Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0W1JY
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| Former ID |
DNC002405
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| Drug Name |
NAPQI
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| Synonyms |
Napqi; Acetimidoquinone; 50700-49-7; N-acetyl-4-benzoquinone imine; N-Acetyl-4-benzoquinoneimine; N-Acetyl-p-benzoquinone imine; N-Acetylbenzoquinoneimine; N-Acetyl-P-benzoquinoneimine; N-Acetyl-p-quinonimine; N-Acetyl-p-benzoquinone; N-(4-oxocyclohexa-2,5-dien-1-ylidene)acetamide; UNII-G6S9BN13TI; CCRIS 5789; N-acetyl-1,4-benzoquinone imine; BRN 2435621; G6S9BN13TI; 2,5-Cyclohexadien-1-one, 4-acetylimino-; N-(4-Oxo-2,5-cyclohexadienylidene)acetamide; CHEBI:29132; N-(4-Oxo-2,5-cyclohexadien-1-ylidene)acetamide; Acetamide, N-(4
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| Drug Type |
Small molecular drug
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| Indication | Autoimmune disease [ICD-11: 4A40-4A45; ICD-10: D84.9, M35.9; ICD-9: 279.4] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C8H7NO2
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| Canonical SMILES |
CC(=O)N=C1C=CC(=O)C=C1
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| InChI |
1S/C8H7NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5H,1H3
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| InChIKey |
URNSECGXFRDEDC-UHFFFAOYSA-N
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| CAS Number |
CAS 50700-49-7
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| PubChem Compound ID | ||||
| PubChem Substance ID |
3157570, 4709584, 8146711, 8176216, 12085919, 14967744, 24891199, 34705623, 49860059, 57312339, 57653880, 74502607, 81065532, 84942668, 103205881, 104332622, 117585715, 125371250, 126602124, 129410431, 135260796, 136345198, 137236550, 142267251, 162078039, 162304369, 178102919, 184560195, 198952612, 204364752, 223516362, 226688208, 252262071, 252354324
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| ChEBI ID |
CHEBI:29132
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Macrophage migration inhibitory factor (MIF) | Target Info | Inhibitor | [2] |
| KEGG Pathway | Tyrosine metabolism | |||
| Phenylalanine metabolism | ||||
| Pathwhiz Pathway | Tyrosine Metabolism | |||
| WikiPathways | Spinal Cord Injury | |||
| Adipogenesis | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6299). | |||
| REF 2 | MIF in autoimmunity and novel therapeutic approaches. Autoimmun Rev. 2009 Jan;8(3):244-9. | |||
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