Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0W8JE
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| Former ID |
DPR000134
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| Drug Name |
Depudecin
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| Synonyms |
(1R)-1-[(2S,3S)-3-[(E)-2-[(3S)-3-[(1R)-1-hydroxyethyl]oxiran-2-yl]ethenyl]oxiran-2-yl]prop-2-en-1-ol; 139508-73-9
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| Drug Type |
Small molecular drug
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Preclinical | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C11H16O4
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| Canonical SMILES |
CC(C1C(O1)C=CC2C(O2)C(C=C)O)O
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| InChI |
1S/C11H16O4/c1-3-7(13)11-9(15-11)5-4-8-10(14-8)6(2)12/h3-13H,1H2,2H3/b5-4+/t6-,7-,8+,9+,10+,11+/m1/s1
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| InChIKey |
DLVJMFOLJOOWFS-INMLLLKOSA-N
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| CAS Number |
CAS 139508-73-9
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:64143
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | HDAC inhibitors repress the polycomb protein BMI1. Cell Cycle. 2010 Jul 15; 9(14): 2722-2730. | |||
| REF 2 | Histone deacetylase inhibitors in cancer therapy: latest developments, trends and medicinal chemistry perspective. Anticancer Agents Med Chem. 2007 Sep;7(5):576-92. | |||
| REF 3 | Anticancer activities of histone deacetylase inhibitors. Nat Rev Drug Discov. 2006 Sep;5(9):769-84. | |||
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