Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0W8OH
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| Former ID |
DIB007480
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| Drug Name |
SKF-96231
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| Drug Type |
Small molecular drug
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| Indication | Asthma [ICD-11: CA23; ICD-10: J45, J45.8; ICD-9: 493] | Terminated | [1] | |
| Company |
SmithKline Beecham plc
|
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| Structure |
 |
Download2D MOL |
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| Formula |
C14H14N4O2
|
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| Canonical SMILES |
CCCOC1=CC=CC=C1C2=NC3=C(C(=O)N2)NC=N3
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| InChI |
1S/C14H14N4O2/c1-2-7-20-10-6-4-3-5-9(10)12-17-13-11(14(19)18-12)15-8-16-13/h3-6,8H,2,7H2,1H3,(H2,15,16,17,18,19)
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| InChIKey |
PQTJTRTXCNZDFT-UHFFFAOYSA-N
|
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| CAS Number |
CAS 119409-07-3
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase 5A (PDE5A) | Target Info | Inhibitor | [2] |
| KEGG Pathway | Purine metabolism | |||
| cGMP-PKG signaling pathway | ||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
| Reactome | cGMP effects | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003084) | |||
| REF 2 | Analogue-based Drug Discovery II. Janos Fischer,C. Robin Ganellin. Page(150). | |||
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