Drug Information
Drug General Information | Top | |||
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Drug ID |
D0WJ1N
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Drug Name |
SRI-63-675
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Synonyms |
109516-82-7; SDZ-63-675
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL
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Formula |
C38H63N2O7P
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Canonical SMILES |
CCCCCCCCCCCCCCCCCCNC(=O)OCC1(CCC(O1)(C)COP(=O)([O-])OCC[N+]2=CC=CC3=CC=CC=C32)C
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InChI |
1S/C38H63N2O7P/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-21-28-39-36(41)44-32-37(2)26-27-38(3,47-37)33-46-48(42,43)45-31-30-40-29-22-24-34-23-19-20-25-35(34)40/h19-20,22-25,29H,4-18,21,26-28,30-33H2,1-3H3,(H-,39,41,42,43)/t37-,38+/m0/s1
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InChIKey |
JANHWNKOVXOFLY-QPPIDDCLSA-N
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CAS Number |
CAS 109516-82-7
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Platelet-activating factor receptor (PTAFR) | Target Info | Modulator | [1] |
KEGG Pathway | Calcium signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
Staphylococcus aureus infection | ||||
NetPath Pathway | IL5 Signaling Pathway | |||
Leptin Signaling Pathway | ||||
Reactome | Class A/1 (Rhodopsin-like receptors) | |||
G alpha (q) signalling events | ||||
Interferon gamma signaling | ||||
WikiPathways | GPCRs, Class A Rhodopsin-like | |||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
Small Ligand GPCRs | ||||
Interferon gamma signaling | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | The effect of SRI 63-675, a competitive platelet-activating factor receptor-antagonist, in the generalized Shwartzman reaction. J Lipid Mediat Cell Signal. 1994 Sep;10(3):229-42. |
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