Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0X0IH
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| Former ID |
DNC010490
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| Drug Name |
BENZYLIMIDAZOLE
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| Synonyms |
1-Benzylimidazole; 1-Benzyl-1H-imidazole; 4238-71-5; N-Benzylimidazole; Imidazole, 1-benzyl-; BENZYLIMIDAZOLE; 1H-Imidazole, 1-(phenylmethyl)-; 1-BENZYL IMIDAZOLE; CCRIS 5821; EINECS 224-200-4; 1-Benzylimidazole, 99%; NSC 217337; NSC 126828; CHEMBL14192; AI3-52572; MLS000069473; KKKDZZRICRFGSD-UHFFFAOYSA-N; MFCD00005296; SMR000059044; 1BN; 1-benzylimdazole; 2afx; 1-benzyl-imidazole; 3pb9; 1-Benzylimidazole (BI); Maybridge3_003880; Opera_ID_1637; SCHEMBL414; ACMC-209jp9; AC1Q28WR; AC1L2U3N; AC1Q4X5Z; AC1Q28WS; KSC492M7H; MLS001424205
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C10H10N2
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| Canonical SMILES |
C1=CC=C(C=C1)CN2C=CN=C2
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| InChI |
1S/C10H10N2/c1-2-4-10(5-3-1)8-12-7-6-11-9-12/h1-7,9H,8H2
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| InChIKey |
KKKDZZRICRFGSD-UHFFFAOYSA-N
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| CAS Number |
CAS 4238-71-5
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Steroid 11-beta-hydroxylase (CYP11B1) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Glucocorticoid biosynthesis | ||||
| Mineralocorticoid biosynthesis | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Steroidogenesis | |||
| Reactome | Glucocorticoid biosynthesis | |||
| Endogenous sterols | ||||
| WikiPathways | Metapathway biotransformation | |||
| Oxidation by Cytochrome P450 | ||||
| Metabolism of steroid hormones and vitamin D | ||||
| Corticotropin-releasing hormone | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2). J Med Chem. 2010 Feb 25;53(4):1712-25. | |||
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