Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0X0ZD
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| Former ID |
DIB008313
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| Drug Name |
EXRD-4605
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| Synonyms |
DIRA-7471; Epoxide hydrolase inhibitors (hypertension); Epoxide hydrolase inhibitors (hypertension), Boehringer Ingelheim
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| Indication | Hypertension [ICD-11: BA00-BA04; ICD-9: 401] | Investigative | [1] | |
| Company |
Boehringer Ingelheim Corp
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| Structure |
 |
Download2D MOL |
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Soluble epoxide hydrolase (EPHX2) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Arachidonic acid metabolism | |||
| Metabolic pathways | ||||
| Peroxisome | ||||
| Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
| WikiPathways | Metapathway biotransformation | |||
| Arachidonate Epoxygenase / Epoxide Hydrolase | ||||
| Arachidonic acid metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Soluble epoxide hydrolase inhibition does not prevent cardiac remodeling and dysfunction after aortic constriction in rats and mice. J Cardiovasc Pharmacol. 2013 Apr;61(4):291-301. | |||
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