Drug Information
Drug General Information | Top | |||
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Drug ID |
D0X2ZW
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Former ID |
DIB020041
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Drug Name |
IKs124
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Synonyms |
IKs124; SCHEMBL6559311; GTPL2591
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL
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Formula |
C18H26N2O3S
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Canonical SMILES |
CCCCN(C1CC(OC2=C1C=C(C=C2)C#N)(C)C)S(=O)(=O)CC
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InChI |
1S/C18H26N2O3S/c1-5-7-10-20(24(21,22)6-2)16-12-18(3,4)23-17-9-8-14(13-19)11-15(16)17/h8-9,11,16H,5-7,10,12H2,1-4H3
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InChIKey |
VTICUGOJGKDYJD-UHFFFAOYSA-N
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Voltage-gated potassium channel Kv7.1 (KCNQ1) | Target Info | Blocker (channel blocker) | [2] |
KEGG Pathway | Adrenergic signaling in cardiomyocytes | |||
Cholinergic synapse | ||||
Gastric acid secretion | ||||
Pancreatic secretion | ||||
Protein digestion and absorption | ||||
Vibrio cholerae infection | ||||
Pathwhiz Pathway | Muscle/Heart Contraction | |||
Reactome | Voltage gated Potassium channels | |||
WikiPathways | SIDS Susceptibility Pathways | |||
Potassium Channels | ||||
miR-targeted genes in muscle cell - TarBase | ||||
miR-targeted genes in lymphocytes - TarBase | ||||
TarBasePathway |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2591). | |||
REF 2 | Heteromeric KCNE2/KCNQ1 potassium channels in the luminal membrane of gastric parietal cells. J Physiol. 2004 Dec 1;561(Pt 2):547-57. |
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