Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0X4JN
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| Former ID |
DIB014095
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| Drug Name |
Pelubiprofen
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| Synonyms |
Pelubi; Rubione; CS-670; DW-330; RS-2131
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| Drug Type |
Small molecular drug
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| Indication | Back pain [ICD-11: ME84.Z] | Approved | [1] | |
| Company |
Sankyo Co Ltd
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| Structure |
 |
Download2D MOL |
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| Formula |
C16H18O3
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| Canonical SMILES |
CC(C1=CC=C(C=C1)C=C2CCCCC2=O)C(=O)O
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| InChI |
1S/C16H18O3/c1-11(16(18)19)13-8-6-12(7-9-13)10-14-4-2-3-5-15(14)17/h6-11H,2-5H2,1H3,(H,18,19)/b14-10+
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| InChIKey |
AUZUGWXLBGZUPP-GXDHUFHOSA-N
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| CAS Number |
CAS 69956-77-0
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prostaglandin G/H synthase (COX) | Target Info | Modulator | [1], [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | Anti-inflammatory effect of pelubiprofen, 2-[4-(oxocyclohexylidenemethyl)-phenyl]propionic acid, mediated by dual suppression of COX activity and LPS-induced inflammatory gene expression via NF- B inactivation. J Cell Biochem. 2011 Dec;112(12):3594-603. | |||
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