Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0X4OW
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| Former ID |
DNC011595
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| Drug Name |
2-Oxa-spiro[4.4]nonan-1-one
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| Synonyms |
2-Oxaspiro[4.4]nonan-1-one; 5732-98-9; 2-oxaspiro[4,4]nonan-1-one; CHEMBL330370; SCHEMBL11055887; CTK1H4141; DTXSID90574422; MolPort-028-950-793; ZINC13734068
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C8H12O2
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| Canonical SMILES |
C1CCC2(C1)CCOC2=O
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| InChI |
1S/C8H12O2/c9-7-8(5-6-10-7)3-1-2-4-8/h1-6H2
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| InChIKey |
PBZONIMHAVOWHW-UHFFFAOYSA-N
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| CAS Number |
CAS 5732-98-9
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
| GABA(A) receptor beta-2 (GABRB2) | Target Info | Inhibitor | [1] | |
| GABA(A) receptor gamma-2 (GABRG2) | Target Info | Inhibitor | [1] | |
| Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Serotonergic synapse | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||
| Iron uptake and transport | ||||
| SIDS Susceptibility Pathways | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Alpha-spirocyclopentyl- and alpha-spirocyclopropyl-gamma-butyrolactones: conformationally constrained derivatives of anticonvulsant and convulsant ... J Med Chem. 1994 Jan 21;37(2):275-86. | |||
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