Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0X7HV
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| Former ID |
DIB010330
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| Drug Name |
ZD-6169
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| Synonyms |
ZD-6169; ZD 6169; UNII-H6UIO70F5E; H6UIO70F5E; Zeneca ZD 6169; LVEDGSIMCSQNNX-INIZCTEOSA-N; ZD6169; 147696-46-6; CHEMBL18861; SCHEMBL4261046; BDBM86249; AC1L4306; ZINC1535218; LS-119034; (2S)-N-(4-benzoylphenyl)-3,3,3-trifluoro-2-hydroxy-2-methylpropanamide
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| Drug Type |
Small molecular drug
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| Indication | Urinary incontinence [ICD-11: MF50.2; ICD-9: 788.3] | Discontinued in Phase 2 | [1] | |
| Company |
AstraZeneca plc
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| Structure |
 |
Download2D MOL |
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| Formula |
C17H14F3NO3
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| Canonical SMILES |
CC(C(=O)NC1=CC=C(C=C1)C(=O)C2=CC=CC=C2)(C(F)(F)F)O
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| InChI |
1S/C17H14F3NO3/c1-16(24,17(18,19)20)15(23)21-13-9-7-12(8-10-13)14(22)11-5-3-2-4-6-11/h2-10,24H,1H3,(H,21,23)/t16-/m0/s1
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| InChIKey |
LVEDGSIMCSQNNX-INIZCTEOSA-N
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| CAS Number |
CAS 147696-46-6
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Potassium channel unspecific (KC) | Target Info | Opener | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006442) | |||
| REF 2 | Effects of ZD6169 and ZD0947, 2 potassium adenosine triphosphate channel openers, on bladder function of spinalized rats. J Urol. 2002 Aug;168(2):837-42. | |||
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