Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0X7WG
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| Drug Name |
US10053465, 12
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| Synonyms |
SCHEMBL9894097; SCHEMBL9927070; SCHEMBL9894098; BDBM246873; US10053465, 12; {trans-3-(4-{[4- {[(2S)-2- (hydroxymethyl) pyrrolidin-1-yl] methyl}-6- (trifluoromethyl) pyridin-2- yl]oxy}piperidin-1- yl)-1-[4-(7H- pyrrolo[2,3- d]pyrimidin-4-yl)- 1H-pyrazol-1- yl]cyclobutyl} acetonitrile
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| Drug Type |
Small molecular drug
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| Structure |
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Download2D MOL |
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| Formula |
C32H36F3N9O2
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| Canonical SMILES |
C1CC(N(C1)CC2=CC(=NC(=C2)OC3CCN(CC3)C4CC(C4)(CC#N)N5C=C(C=N5)C6=C7C=CNC7=NC=N6)C(F)(F)F)CO
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| InChI |
1S/C32H36F3N9O2/c33-32(34,35)27-12-21(17-43-9-1-2-23(43)19-45)13-28(41-27)46-25-4-10-42(11-5-25)24-14-31(15-24,6-7-36)44-18-22(16-40-44)29-26-3-8-37-30(26)39-20-38-29/h3,8,12-13,16,18,20,23-25,45H,1-2,4-6,9-11,14-15,17,19H2,(H,37,38,39)/t23-,24?,31?/m0/s1
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| InChIKey |
WQXUGBZSZWSUTM-VVTYCJQISA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | TYRO3 tyrosine kinase receptor (TYRO3) | Target Info | Inhibitor | [1] |
| Target's Patent Info | TYRO3 tyrosine kinase receptor (TYRO3) | Target's Patent Info | [1] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Fused bicyclic 1,2,4-triazine compounds as TAM inhibitors. US9708333. | |||
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