Drug Information
Drug General Information | Top | |||
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Drug ID |
D0X9OV
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Former ID |
DNC006906
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Drug Name |
2-amino-3,4',5-trimethoxy-(Z)-stillbene
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Synonyms |
CHEMBL216433; SCHEMBL4224804
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C17H19NO3
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Canonical SMILES |
COC1=CC=C(C=C1)C=CC2=C(C(=CC(=C2)OC)OC)N
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InChI |
1S/C17H19NO3/c1-19-14-8-5-12(6-9-14)4-7-13-10-15(20-2)11-16(21-3)17(13)18/h4-11H,18H2,1-3H3/b7-4-
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InChIKey |
WCORNZIRKFTEOF-DAXSKMNVSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Tubulin beta (TUBB) | Target Info | Inhibitor | [1] |
Tubulin beta-2 chain (TUBB2) | Target Info | Inhibitor | [1] | |
KEGG Pathway | Phagosome | |||
Gap junction | ||||
Pathogenic Escherichia coli infection | ||||
NetPath Pathway | FSH Signaling Pathway | |||
TCR Signaling Pathway | ||||
EGFR1 Signaling Pathway | ||||
Panther Pathway | Cytoskeletal regulation by Rho GTPase | |||
Huntington disease | ||||
Reactome | Regulation of PLK1 Activity at G2/M Transition | |||
Loss of Nlp from mitotic centrosomes | ||||
Recruitment of mitotic centrosome proteins and complexes | ||||
Loss of proteins required for interphase microtubule organization?from the centrosome | ||||
Anchoring of the basal body to the plasma membrane | ||||
WikiPathways | Parkin-Ubiquitin Proteasomal System pathway | |||
Pathogenic Escherichia coli infection | ||||
Mitotic G2-G2/M phases |
References | Top | |||
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REF 1 | 2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents. J Med Chem. 2006 Oct 19;49(21):6412-5. |
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