Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0XJ0P
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| Former ID |
DIB013245
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| Drug Name |
BCX-140
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| Synonyms |
4-(Acetylamino)-3-guanidinobenzoic acid; BANA-113; UNII-V02KF5948M; BANA 113; CHEMBL55440; 170447-93-5; V02KF5948M; Benzoic acid, 4-(acetylamino)-3-((aminoiminomethyl)amino)-; 4-acetamido-3-guanidino-benzoic acid; Benzoic acid, 4-(acetylamino)-3-[(aminoiminomethyl)amino]-; 1inf; AC1L9JI9; 4-acetamido-3-(diaminomethylideneamino)benzoic acid; SCHEMBL141675; BDBM4707; UDQJOWCVSMIZJP-UHFFFAOYSA-N; 4-Acetylamino-3-guanidino-benzoic acid; 3-carbamimidamido-4-acetamidobenzoic acid; 3-(2,2-diaminoimino)-4-methylcarboxamidobenzoate; BANA-113; BANA-153; BANA-205; BANA-206; Neuraminidase inhibitors, BioCryst; 4-(Acetylamino)-3-Guanidinobenzoic Acid
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| Drug Type |
Small molecular drug
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| Indication | Influenza virus infection [ICD-11: 1E30-1E32] | Terminated | [1] | |
| Company |
BioCryst Pharmaceuticals Inc
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| Structure |
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Download2D MOL |
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| Formula |
C10H12N4O3
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| Canonical SMILES |
CC(=O)NC1=C(C=C(C=C1)C(=O)O)N=C(N)N
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| InChI |
1S/C10H12N4O3/c1-5(15)13-7-3-2-6(9(16)17)4-8(7)14-10(11)12/h2-4H,1H3,(H,13,15)(H,16,17)(H4,11,12,14)
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| InChIKey |
UDQJOWCVSMIZJP-UHFFFAOYSA-N
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| CAS Number |
CAS 170447-93-5
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Influenza Neuraminidase (Influ NA) | Target Info | Inhibitor | [2], [3], [4] |
| KEGG Pathway | Other glycan degradation | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006335) | |||
| REF 2 | CN patent application no. 104447481, Benzoic acid thiourea anti-influenza virus compounds as well as preparation method and use thereof. | |||
| REF 3 | Neuraminidase inhibitors: zanamivir and oseltamivir. Ann Pharmacother. 2001 Jan;35(1):57-70. | |||
| REF 4 | DrugBank 3.0: a comprehensive resource for 'omics' research on drugs. Nucleic Acids Res. 2011 Jan;39(Database issue):D1035-41. | |||
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