Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0XR4J
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| Former ID |
DNC014229
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| Drug Name |
H-Phe-Phe-NH2
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| Synonyms |
CHEMBL108438; 15893-46-6; Phe-phe-amide; Phenylalanylphenylalanylamide; L-Phe-L-phe-amide; H-Phe-Phe-NH2; L-Phenylalanine-L-phenylalanylamide; L-Phe-L-Phe-NH2; AC1L38WX; XXPXQEQOAZMUDD-HOTGVXAUSA-N; L-Phenylalaninamide, L-phenylalanyl-; BDBM50188489; (S)-2-Amino-N-((S)-1-carbamoyl-2-phenyl-ethyl)-3-phenyl-propionamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C18H21N3O2
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| Canonical SMILES |
C1=CC=C(C=C1)CC(C(=O)NC(CC2=CC=CC=C2)C(=O)N)N
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| InChI |
1S/C18H21N3O2/c19-15(11-13-7-3-1-4-8-13)18(23)21-16(17(20)22)12-14-9-5-2-6-10-14/h1-10,15-16H,11-12,19H2,(H2,20,22)(H,21,23)/t15-,16-/m0/s1
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| InChIKey |
XXPXQEQOAZMUDD-HOTGVXAUSA-N
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| CAS Number |
CAS 15893-46-6
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Substance-P receptor (TACR1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Measles | ||||
| Panther Pathway | CCKR signaling map ST | |||
| Reactome | G alpha (q) signalling events | |||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| Spinal Cord Injury | ||||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Discovery of dipeptides with high affinity to the specific binding site for substance P1-7. J Med Chem. 2010 Mar 25;53(6):2383-9. | |||
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