Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0XT7O
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| Drug Name |
Pyrazolo[1,5-a]pyrimidine derivative 29
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| Synonyms |
PMID25470667-Compound-Figure5-18
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| Drug Type |
Small molecular drug
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| Company |
GLAXOSMITHKLINE LLGLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED QIN, Donghui CHEUNG, Mui JOSHI, Hemant TANGIRALA, Raghuram BETHI, Sridhar, Reddy
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| Structure |
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Download2D MOL |
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| Formula |
C17H17N5
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| Canonical SMILES |
CCCN1C=CC2=C1C=CC(=C2)C3=C(N4C(=CC=N4)N=C3)N
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| InChI |
1S/C17H17N5/c1-2-8-21-9-6-13-10-12(3-4-15(13)21)14-11-19-16-5-7-20-22(16)17(14)18/h3-7,9-11H,2,8,18H2,1H3
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| InChIKey |
WYJQPMFWZLKCBR-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Diacylglycerol acyltransferase 1 (DGAT1) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Diacylglycerol acyltransferase 1 (DGAT1) | Target's Patent Info | [1] | |
| BioCyc | Triacylglycerol biosynthesis | |||
| KEGG Pathway | Glycerolipid metabolism | |||
| Retinol metabolism | ||||
| Metabolic pathways | ||||
| Fat digestion and absorption | ||||
| Pathwhiz Pathway | Retinol Metabolism | |||
| Reactome | Acyl chain remodeling of DAG and TAG | |||
| Triglyceride Biosynthesis | ||||
| WikiPathways | Vitamin A and Carotenoid Metabolism | |||
| Statin Pathway | ||||
| Triacylglyceride Synthesis | ||||
| Glycerophospholipid biosynthesis | ||||
| Fatty acid, triacylglycerol, and ketone body metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Acyltransferase inhibitors: a patent review (2010-present).Expert Opin Ther Pat. 2015 Feb;25(2):145-58. | |||
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