Drug Information
Drug General Information | Top | |||
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Drug ID |
D0XU4Y
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Former ID |
DNC011363
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Drug Name |
NSC-66209
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Synonyms |
5407-46-5; Methyl fluorone black; 2,6,7-Trihydroxy-9-methylxanthen-3-one; NSC-66209; 2,6,7-Trihydroxy-9-methyl-xanthen-3-one; NSC 5426; UNII-KQC69H1NAG; KQC69H1NAG; 3H-Xanthen-3-one, 2,6,7-trihydroxy-9-methyl-; MLS000736515; MLS000123248; CHEMBL175266; 2,6,7-trihydroxy-9-methyl-3H-xanthen-3-one; NSC5426; NSC66209; 9-Methyl-2,3,7-trihydroxy-6-fluorone Hemisulfate; ST057760; SMR000123893; BAS 00532150; 9-METHYL-2,3,7-TRIHYDROXY-6-FLUORONE; EINECS 226-468-8; NSC 66209; AC1Q69RP; AC1L2IJ2; cid_72721; SCHEMBL2781454; CTK4J9473
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C14H10O5
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Canonical SMILES |
CC1=C2C=C(C(=O)C=C2OC3=CC(=C(C=C13)O)O)O
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InChI |
1S/C14H10O5/c1-6-7-2-9(15)11(17)4-13(7)19-14-5-12(18)10(16)3-8(6)14/h2-5,15-17H,1H3
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InChIKey |
TZVNNUHRZXQCHM-UHFFFAOYSA-N
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CAS Number |
CAS 5407-46-5
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Candida Mannose-6-phosphate isomerase (Candi PMI1) | Target Info | Inhibitor | [1] |
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) | Target Info | Inhibitor | [1] | |
KEGG Pathway | PI3K-Akt signaling pathway | |||
MicroRNAs in cancer | ||||
NetPath Pathway | TCR Signaling Pathway | |||
Panther Pathway | Apoptosis signaling pathway | |||
CCKR signaling map ST | ||||
Pathway Interaction Database | E2F transcription factor network | |||
Direct p53 effectors | ||||
IL6-mediated signaling events | ||||
HIF-1-alpha transcription factor network | ||||
WikiPathways | Apoptosis | |||
miR-targeted genes in muscle cell - TarBase | ||||
miR-targeted genes in lymphocytes - TarBase | ||||
miR-targeted genes in leukocytes - TarBase | ||||
Apoptosis Modulation and Signaling |
References | Top | |||
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REF 1 | In silico identification and biochemical evaluation of novel inhibitors of NRH:quinone oxidoreductase 2 (NQO2). Bioorg Med Chem Lett. 2010 Dec 15;20(24):7331-6. |
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