Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Y3DR
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| Former ID |
DNC012280
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| Drug Name |
1-(1-Benzo[b]thiophen-2-yl-cyclopentyl)-azepane
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| Synonyms |
CHEMBL18025; AC1LCXWM; 1-(1-Benzo[b]thiophen-2-yl-cyclopentyl)-azepane; XZXHOFZYYWGLCJ-UHFFFAOYSA-N; BDBM50040198; 1-[1-(1-Benzothien-2-yl)cyclopentyl]azepane #; 1-[1-(1-benzothiophen-2-yl)cyclopentyl]azepane; Thionaphthene, 2-[1-(1-azacycloheptyl)cyclopentyl]-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C19H25NS
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| Canonical SMILES |
C1CCCN(CC1)C2(CCCC2)C3=CC4=CC=CC=C4S3
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| InChI |
1S/C19H25NS/c1-2-8-14-20(13-7-1)19(11-5-6-12-19)18-15-16-9-3-4-10-17(16)21-18/h3-4,9-10,15H,1-2,5-8,11-14H2
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| InChIKey |
XZXHOFZYYWGLCJ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Dopamine transporter (DAT) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Dopaminergic synapse | |||
| Parkinson's disease | ||||
| Cocaine addiction | ||||
| Amphetamine addiction | ||||
| Alcoholism | ||||
| Panther Pathway | Adrenaline and noradrenaline biosynthesis | |||
| Parkinson disease | ||||
| Dopamine receptor mediated signaling pathway | ||||
| Pathway Interaction Database | Alpha-synuclein signaling | |||
| Reactome | Na+/Cl- dependent neurotransmitter transporters | |||
| WikiPathways | Monoamine Transport | |||
| NRF2 pathway | ||||
| Dopaminergic Neurogenesis | ||||
| Parkinsons Disease Pathway | ||||
| Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | ||||
| Neurotransmitter Clearance In The Synaptic Cleft | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and biological evaluation of 1-[1-(2-benzo[b]thienyl)cyclohexyl]piperidine homologues at dopamine-uptake and phencyclidine- and sigma-bin... J Med Chem. 1993 Apr 30;36(9):1188-93. | |||
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