Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0Y7AN
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| Former ID |
DNC003618
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| Drug Name |
2-(3-Mercapto-propyl)-pentanedioic acid
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| Synonyms |
2-(3-mercaptopropyl)pentanedioic acid; 2-MPPA; 2-(3-sulfanylpropyl)pentanedioic Acid; 254737-29-6; CHEMBL303352; Pentanedioic acid, 2-(3-mercaptopropyl)-; 2-[3-mercaptopropyl]pentanedioic acid; GPI 5693; SCHEMBL787800; CTK0J4030; BDBM17755; FNLNSQHJKVQCBP-UHFFFAOYSA-N; MolPort-035-765-922; pentanedioic acid analogue, (RS)-3; AKOS024458465
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C8H14O4S
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| Canonical SMILES |
C(CC(CCC(=O)O)C(=O)O)CS
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| InChI |
1S/C8H14O4S/c9-7(10)4-3-6(8(11)12)2-1-5-13/h6,13H,1-5H2,(H,9,10)(H,11,12)
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| InChIKey |
FNLNSQHJKVQCBP-UHFFFAOYSA-N
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| CAS Number |
CAS 254737-29-6
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glutamate carboxypeptidase II (GCPII) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Alanine, aspartate and glutamate metabolism | |||
| Metabolic pathways | ||||
| Vitamin digestion and absorption | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| TNFalpha Signaling Pathway | ||||
| Reactome | Amino acid synthesis and interconversion (transamination) | |||
| WikiPathways | One Carbon Metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and biological evaluation of thiol-based inhibitors of glutamate carboxypeptidase II: discovery of an orally active GCP II inhibitor. J Med Chem. 2003 May 8;46(10):1989-96. | |||
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