Drug Information
Drug General Information | Top | |||
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Drug ID |
D0Y7RB
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Former ID |
DNC004696
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Drug Name |
3-[6-Methyl-indan-(1Z)-ylidenemethyl]-pyridine
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Synonyms |
(3-Pyridylmethylene)indane 21b; CHEMBL366570; BDBM8605; AC1O705D; 3-[(Z)-(6-methyl-2,3-dihydroinden-1-ylidene)methyl]pyridine
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C16H15N
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Canonical SMILES |
CC1=CC2=C(CCC2=CC3=CN=CC=C3)C=C1
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InChI |
1S/C16H15N/c1-12-4-5-14-6-7-15(16(14)9-12)10-13-3-2-8-17-11-13/h2-5,8-11H,6-7H2,1H3/b15-10-
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InChIKey |
INXZXCKRUCKCJE-GDNBJRDFSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Aromatase (CYP19A1) | Target Info | Inhibitor | [1] |
BioCyc | Superpathway of steroid hormone biosynthesis | |||
Estradiol biosynthesis II | ||||
Estradiol biosynthesis I | ||||
KEGG Pathway | Steroid hormone biosynthesis | |||
Metabolic pathways | ||||
Ovarian steroidogenesis | ||||
NetPath Pathway | FSH Signaling Pathway | |||
Panther Pathway | Androgen/estrogene/progesterone biosynthesis | |||
Pathwhiz Pathway | Androgen and Estrogen Metabolism | |||
Reactome | Endogenous sterols | |||
WikiPathways | Metapathway biotransformation | |||
Tryptophan metabolism | ||||
Oxidation by Cytochrome P450 | ||||
Ovarian Infertility Genes | ||||
Metabolism of steroid hormones and vitamin D | ||||
FSH signaling pathway | ||||
Integrated Breast Cancer Pathway | ||||
Phase 1 - Functionalization of compounds |
References | Top | |||
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REF 1 | Synthesis and evaluation of (pyridylmethylene)tetrahydronaphthalenes/-indanes and structurally modified derivatives: potent and selective inhibitor... J Med Chem. 2005 Mar 10;48(5):1563-75. |
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