Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0Y8LO
|
|||
Former ID |
DNC000448
|
|||
Drug Name |
Clik60
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Cathepsin S (CTSS) | Target Info | Inhibitor | [1] |
KEGG Pathway | Lysosome | |||
Phagosome | ||||
Antigen processing and presentation | ||||
Tuberculosis | ||||
NetPath Pathway | Leptin Signaling Pathway | |||
IL2 Signaling Pathway | ||||
Reactome | Endosomal/Vacuolar pathway | |||
Degradation of the extracellular matrix | ||||
Trafficking and processing of endosomal TLR | ||||
Assembly of collagen fibrils and other multimeric structures | ||||
MHC class II antigen presentation | ||||
WikiPathways | Class I MHC mediated antigen processing & presentation | |||
Trafficking and processing of endosomal TLR |
References | Top | |||
---|---|---|---|---|
REF 1 | Cathepsin S inhibitor prevents autoantigen presentation and autoimmunity. J Clin Invest. 2002 Aug;110(3):361-9. |
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