Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0YK6K
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| Drug Name |
PMID27376512-Compound-Table1Example30
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| Drug Type |
Small molecular drug
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| Company |
IKERCHEM S L [ESUNIV DEL PA S VASCO [ES]
|
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| Structure |
 |
Download2D MOL |
||
| Formula |
C32H29NO11
|
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| Canonical SMILES |
CC(=O)OC1=C(C=C(C=C1)C2=CN(C3=C2C(=CC(=C3)OC)OC)CC(=O)C4=CC(=C(C=C4)OC(=O)C)OC(=O)C)OC(=O)C
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| InChI |
1S/C32H29NO11/c1-17(34)41-27-9-7-21(11-29(27)43-19(3)36)24-15-33(25-13-23(39-5)14-31(40-6)32(24)25)16-26(38)22-8-10-28(42-18(2)35)30(12-22)44-20(4)37/h7-15H,16H2,1-6H3
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| InChIKey |
NMWWCTXMWYUUNT-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | DNA [cytosine-5]-methyltransferase 1 (DNMT1) | Target Info | Inhibitor | [1] |
| Target's Patent Info | DNA [cytosine-5]-methyltransferase 1 (DNMT1) | Target's Patent Info | [1] | |
| KEGG Pathway | Cysteine and methionine metabolism | |||
| Metabolic pathways | ||||
| MicroRNAs in cancer | ||||
| Pathwhiz Pathway | Methionine Metabolism | |||
| Pathway Interaction Database | Regulation of retinoblastoma protein | |||
| Reactome | PRC2 methylates histones and DNA | |||
| NoRC negatively regulates rRNA expression | ||||
| DNA methylation | ||||
| WikiPathways | Trans-sulfuration and one carbon metabolism | |||
| Retinoblastoma (RB) in Cancer | ||||
| One Carbon Metabolism | ||||
| Trans-sulfuration pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | DNA methyltransferase inhibitors: an updated patent review (2012-2015).Expert Opin Ther Pat. 2016 Sep;26(9):1017-30. | |||
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