Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0YO7Y
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| Former ID |
DIB007042
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| Drug Name |
DAS-181
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| Synonyms |
Fludase; NEX-DAS-181; Enzyme-based therapy (Tosap, influenza), NexBio
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| Indication | Influenza virus infection [ICD-11: 1E30-1E32] | Phase 2 | [1] | |
| Company |
Nexbio
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Influenza Neuraminidase (Influ NA) | Target Info | Inhibitor | [1], [2] |
| KEGG Pathway | Other glycan degradation | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Inhibition of neuraminidase inhibitor-resistant influenza virus by DAS181, a novel sialidase fusion protein. PLoS One. 2009 Nov 6;4(11):e7838. | |||
| REF 2 | Neuraminidase inhibitors: zanamivir and oseltamivir. Ann Pharmacother. 2001 Jan;35(1):57-70. | |||
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