Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0Z0EH
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| Former ID |
DIB009038
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| Drug Name |
PheTQS
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| Synonyms |
Alpha7 nicotinic acetylcholine receptor positive allosteric modulators (PAMs) (CNS disorders), GlaxoSmithKline; Alpha7 nicotinic acetylcholine receptor positive allosteric modulators (PAMs) (CNS disorders), Proximagen
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| Indication | Central nervous system disease [ICD-11: 8A04-8D87; ICD-10: G00-G99] | Investigative | [1] | |
| Company |
GlaxoSmithKline plc
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| Structure |
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Download2D MOL |
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Neuronal acetylcholine receptor alpha-7 (CHRNA7) | Target Info | Modulator | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Cholinergic synapse | ||||
| Nicotine addiction | ||||
| Chemical carcinogenesis | ||||
| Panther Pathway | Alzheimer disease-amyloid secretase pathway | |||
| Nicotinic acetylcholine receptor signaling pathway | ||||
| Reactome | Highly calcium permeable postsynaptic nicotinic acetylcholine receptors | |||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 468). | |||
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