Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Z2MX
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| Drug Name |
Acyl oxymethyl acrylamide ester derivative 1
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| Synonyms |
PMID27977313-Compound-26
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| Drug Type |
Small molecular drug
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| Company |
INST CHEMII ORGANICZNEJ POLSKIEJ AKADEMII NAUK [PLWARSZAWSKI UNIV MEDYCZNY [PL]
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| Structure |
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Download2D MOL |
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| Formula |
C23H26F6N2O6
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| Canonical SMILES |
CCOC(=O)CNC(=O)C(CC(C)C)NC(=O)C(=C)COC(=O)C1=C(C=CC=C1C(F)(F)F)C(F)(F)F
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| InChI |
1S/C23H26F6N2O6/c1-5-36-17(32)10-30-20(34)16(9-12(2)3)31-19(33)13(4)11-37-21(35)18-14(22(24,25)26)7-6-8-15(18)23(27,28)29/h6-8,12,16H,4-5,9-11H2,1-3H3,(H,30,34)(H,31,33)
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| InChIKey |
PIBIRGYHHYAZIQ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cytoplasmic thioredoxin reductase (TXNRD1) | Target Info | Inhibitor | [1] |
| Glutathione reductase (GR) | Target Info | Inhibitor | [1] | |
| Target's Patent Info | Cytoplasmic thioredoxin reductase (TXNRD1) | Target's Patent Info | [1] | |
| Glutathione reductase (GR) | Target's Patent Info | [1] | ||
| BioCyc | Glutathione redox reactions II | |||
| Glutathione redox reactions I | ||||
| KEGG Pathway | Glutathione metabolism | |||
| Thyroid hormone synthesis | ||||
| Pathwhiz Pathway | Glutamate Metabolism | |||
| Glutathione Metabolism | ||||
| WikiPathways | Metapathway biotransformation | |||
| Sulfation Biotransformation Reaction | ||||
| Oxidative Stress | ||||
| NRF2 pathway | ||||
| Nuclear Receptors Meta-Pathway | ||||
| Selenium Micronutrient Network | ||||
| Glutathione metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Thioredoxin reductase inhibitors: a patent review.Expert Opin Ther Pat. 2017 May;27(5):547-556. | |||
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