Drug Information
Drug General Information | Top | |||
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Drug ID |
D0Z5HB
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Former ID |
DIB009972
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Drug Name |
FH-510
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Synonyms |
Fh-510; CCRIS 6870; UNII-J02GJE6S84; FH 510; 139304-28-2; J02GJE6S84; 9H-Carbazole-4-ethanamine, 5,8-dimethyl-N,N-dipropyl-, monohydrochloride; AC1L36MK; SCHEMBL467264; DTXSID00161004; LS-189199; N-[2-(5,8-dimethyl-9H-carbazol-4-yl)ethyl]-N-propylpropan-1-amine hydrochloride
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Drug Type |
Small molecular drug
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Indication | Psychotic disorder [ICD-11: 6A20-6A25] | Terminated | [1] | |
Company |
Taisho Pharmaceutical Co Ltd
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Structure |
Download2D MOL |
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Formula |
C22H31ClN2
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Canonical SMILES |
CCCN(CCC)CCC1=C2C(=CC=C1)NC3=C(C=CC(=C23)C)C.Cl
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InChI |
1S/C22H30N2.ClH/c1-5-13-24(14-6-2)15-12-18-8-7-9-19-21(18)20-16(3)10-11-17(4)22(20)23-19;/h7-11,23H,5-6,12-15H2,1-4H3;1H
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InChIKey |
NSLYKDHGJLVNIJ-UHFFFAOYSA-N
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CAS Number |
CAS 139304-28-2
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Opioid receptor sigma 1 (OPRS1) | Target Info | Modulator | [2], [3], [4] |
WikiPathways | miR-targeted genes in squamous cell - TarBase | |||
miR-targeted genes in lymphocytes - TarBase |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002069) | |||
REF 2 | FH-510, a potent and selective ligand for rat brain sigma recognition sites. Eur J Pharmacol. 1993 Jul 6;238(1):89-92. | |||
REF 3 | Antitussives and substance abuse. Subst Abuse Rehabil. 2013 Nov 6;4:75-82. | |||
REF 4 | Dextromethorphan antagonizes the acute depletion of brain serotonin by p-chloroamphetamine and H75/12 in rats. Brain Res. 1992 Oct 30;594(2):323-6. |
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