Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Z5NP
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| Drug Name |
Phenylpyrrolidinone derivative 4
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| Synonyms |
PMID27646439-Compound-8
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| Drug Type |
Small molecular drug
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| Company |
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED
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| Structure |
 |
Download2D MOL |
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| Formula |
C23H18F3N5O
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| Canonical SMILES |
CN1C=C(C2=C(N=CN=C21)N)C3=C(C=C(C=C3)N4CCC(C4=O)C5=CC(=CC(=C5)F)F)F
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| InChI |
1S/C23H18F3N5O/c1-30-10-18(20-21(27)28-11-29-22(20)30)17-3-2-15(9-19(17)26)31-5-4-16(23(31)32)12-6-13(24)8-14(25)7-12/h2-3,6-11,16H,4-5H2,1H3,(H2,27,28,29)
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| InChIKey |
JZSDPOSETBCTOH-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | PRKR-like endoplasmic reticulum kinase (PERK) | Target Info | Inhibitor | [1] |
| Target's Patent Info | PRKR-like endoplasmic reticulum kinase (PERK) | Target's Patent Info | [1] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Protein kinase R(PKR)-like endoplasmic reticulum kinase (PERK) inhibitors: a patent review (2010-2015).Expert Opin Ther Pat. 2017 Jan;27(1):37-48. | |||
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